Improving imaging and treatment for ovarian cancer
Multimodal Imaging and Therapy of Ovarian Cancer
This study is working on a new way to find and treat ovarian cancer, especially for patients with advanced disease, by using special tiny particles that help doctors see tumors better before and during surgery, which could lead to better outcomes for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10675568 on NIH RePORTER |
What this research studies
This research focuses on enhancing the detection and treatment of ovarian cancer, particularly for patients with metastatic intra-peritoneal disease. It aims to develop a theranostic agent that allows for in vivo imaging of tumors before surgery and helps visualize them during surgery using near-infrared imaging. The approach utilizes advanced dual-Gd liposomal nanoparticles to improve MRI contrast and incorporates FDA-approved indocyanine green for better tumor visualization. By improving surgical outcomes and potentially enabling treatment of tumors in difficult locations, this research seeks to address significant limitations in current ovarian cancer therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with ovarian cancer, particularly those with metastatic intra-peritoneal disease.
Not a fit: Patients with early-stage ovarian cancer or those whose cancer has not spread may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective surgical interventions and improved survival rates for ovarian cancer patients.
How similar studies have performed: Other research has shown promise with similar imaging and treatment approaches, indicating potential for success in this novel application.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Kundra, Vikas — University of Maryland Baltimore
- Study coordinator: Kundra, Vikas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.