Improving identification methods for substance use disorders using genetic data
Official title: Framework to Accelerate Substance Use Disorder Genetic Studies through Customizable, EHR-Based Precision Phenotyping
Funded at Vanderbilt University Medical Center · NIH-11263104 · Data updated 2026-11-12
This study is working on a new way to better identify substance use disorders by using health records and genetic information, which could help doctors find more accurate treatments and support for people struggling with these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 1, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $525,000 |
| NIH project number | 7DP1DA056667-04 |
| Project ID | NIH-11263104 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been diagnosed with or are at risk for substance use disorders.
✕Less likely to help
Patients who do not have a history of substance use or are not at risk for substance use disorders may not benefit from this research.
What this research studies
This research aims to develop a new method for accurately identifying substance use disorders (SUD) by utilizing electronic health records (EHR) and genetic data. The approach focuses on creating a customizable phenotyping framework that can integrate various data sources, such as billing codes and medication information, to provide a more nuanced understanding of SUD. By evaluating this framework across multiple organizations, the research seeks to enhance the identification of SUD cases and support genetic studies that could lead to better prevention and treatment strategies. Ultimately, this work aims to contribute to the development of clinical tools that can improve patient care.
Why it matters
Potential benefit: If successful, this research could lead to more accurate identification and understanding of substance use disorders, resulting in improved prevention and treatment options for patients.
How similar studies have gone: Other research has shown promise in using electronic health records and genetic data for improving disease identification, suggesting that this approach could be effective.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Jeffery, Alvin Dean — Vanderbilt University Medical Center
- Study coordinator: Jeffery, Alvin Dean
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.