Improving ICU care for people with respiratory failure

Promoting Change in Practice for Respiratory Failure: the PRECIPICE Study

NIH-funded research New York University · NIH-11073082

This project aims to change ICU practices to help Hispanic patients with respiratory failure survive and recover better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11073082 on NIH RePORTER

What this research studies

Researchers will compare recovery and six-month outcomes for Hispanic and non-Hispanic patients who survived respiratory failure using a patient registry. They will visit ten U.S. hospitals to observe how ICUs deliver sedation and physical therapy and collect information from clinicians through interviews and surveys. The team will look for care practices that may lead to deeper sedation or less physical therapy for Hispanic patients and identify opportunities to change those practices. Findings will be used to guide improvements in ICU care that could reduce death and long-term disability after respiratory failure.

Who could benefit from this research

Good fit: Adults who have experienced respiratory failure and required ICU care or mechanical ventilation—especially Hispanic patients—are the main group whose outcomes are being examined.

Not a fit: People without respiratory failure, children, or those not treated at participating hospitals are unlikely to directly benefit from this specific project.

Why it matters

Potential benefit: If successful, the work could reduce deaths and improve long-term function for Hispanic patients after respiratory failure by changing ICU sedation and rehabilitation practices.

How similar studies have performed: Prior research shows lighter sedation and early physical therapy can improve survival and function, but using those approaches specifically to reduce ethnic disparities is a newer focus.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.