Improving ICU care for people with respiratory failure
Official title: Promoting Change in Practice for Respiratory Failure: the PRECIPICE Study
Funded at New York University · NIH-11073082 · Data updated 2026-11-12
This project aims to change ICU practices to help Hispanic patients with respiratory failure survive and recover better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 15, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $648,089 |
| NIH project number | 5R01HL157361-04 |
| Project ID | NIH-11073082 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who have experienced respiratory failure and required ICU care or mechanical ventilation—especially Hispanic patients—are the main group whose outcomes are being examined.
✕Less likely to help
People without respiratory failure, children, or those not treated at participating hospitals are unlikely to directly benefit from this specific project.
What this research studies
Researchers will compare recovery and six-month outcomes for Hispanic and non-Hispanic patients who survived respiratory failure using a patient registry. They will visit ten U.S. hospitals to observe how ICUs deliver sedation and physical therapy and collect information from clinicians through interviews and surveys. The team will look for care practices that may lead to deeper sedation or less physical therapy for Hispanic patients and identify opportunities to change those practices. Findings will be used to guide improvements in ICU care that could reduce death and long-term disability after respiratory failure.
Why it matters
Potential benefit: If successful, the work could reduce deaths and improve long-term function for Hispanic patients after respiratory failure by changing ICU sedation and rehabilitation practices.
How similar studies have gone: Prior research shows lighter sedation and early physical therapy can improve survival and function, but using those approaches specifically to reduce ethnic disparities is a newer focus.
Where this research is happening
-
New York University
New York, United States Active
Researchers
- Principal investigator: Armstrong-Hough, Mari — New York University
- Study coordinator: Armstrong-Hough, Mari
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A big study using hospital records to figure out which patients with acute respiratory failure and sepsis do best when admitted to ICUs versus general wards.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.