Improving how we understand protein functions using community collaboration
Official title: Fine-grained Annotation of the Protein Universe through a Community of Practice
Funded at Iowa State University · NIH-10978845 · Data updated 2026-11-12
This study is all about figuring out what proteins do in our bodies, which can help scientists discover new treatments, and it brings together experts to create better tools for understanding these proteins.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa State University NIH-funded |
| Lab location | 1 site (Ames, United States) |
| Project start | September 25, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $465,756 |
| NIH project number | 1R01GM145937-01A1 |
| Project ID | NIH-10978845 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with genetic conditions or diseases linked to protein function abnormalities.
✕Less likely to help
Patients with conditions unrelated to protein functions or those not requiring genetic insights may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the understanding of protein functions, which is crucial for biological discoveries. It involves a collaborative effort among computational biologists, data scientists, and biocurators to develop better algorithms for predicting protein functions. By engaging a wider community and creating open-source software, the project aims to improve the accuracy of protein function annotations. Patients may benefit indirectly as this research could lead to advancements in treatments based on a better understanding of proteins.
Why it matters
Potential benefit: If successful, this research could lead to more accurate protein function predictions, potentially improving the development of targeted therapies for various diseases.
How similar studies have gone: Previous research has shown success in improving protein function prediction through community-driven approaches, indicating a promising avenue for this project.
Where this research is happening
-
Iowa State University
Ames, United States Active
Researchers
- Principal investigator: Friedberg, Iddo — Iowa State University
- Study coordinator: Friedberg, Iddo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.