Improving How We Understand Brain Scans

Inter-modal Coupling Image Analytics

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-11128822

This project creates new ways to analyze different types of brain scans to better understand how brain structure and function are connected, especially in young people with mental health conditions.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11128822 on ClinicalTrials.gov

What this research studies

Doctors often use many types of brain scans to get a full picture of someone's brain, looking at both its structure and how it works. This project is building advanced statistical tools to better understand how these different types of brain images relate to each other. These new tools will help us uncover complex connections within individual brains and see how conditions like mental illness might affect these brain networks. The goal is to improve our ability to link specific brain patterns to challenges like executive dysfunction in young people.

Who could benefit from this research

Good fit: Young people experiencing mental health conditions, particularly those with difficulties in executive functions like planning or focus, might eventually benefit from the insights gained from this work.

Not a fit: Patients seeking immediate new treatments or direct clinical interventions will not directly benefit from this foundational methods development.

Why it matters

Potential benefit: If successful, these new analytical methods could lead to more precise ways to understand brain conditions and potentially guide better treatments for mental health challenges in young people.

How similar studies have performed: This project proposes novel statistical methods to address current gaps in analyzing complex brain imaging data, moving beyond existing ad hoc solutions.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.