Improving how we understand and treat swallowing problems
Evolution of the Chicago Classification: Bridging Physiology and Mechanics
This work aims to improve how doctors diagnose and treat common swallowing difficulties and acid reflux by looking at how the esophagus works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11163519 on NIH RePORTER |
What this research studies
Many people experience trouble swallowing or acid reflux, which can greatly affect their quality of life. This project is exploring new ways to understand these issues by focusing on how the esophagus moves food and liquid, not just the muscles. We are building on the 'Chicago Classification,' a system already used worldwide, to make it even better. By combining insights into how the esophagus responds to food and liquid, we hope to create more accurate ways to identify the root causes of swallowing problems.
Who could benefit from this research
Good fit: This research is relevant for patients experiencing chronic swallowing difficulties (dysphagia), acid reflux (GERD), or specific esophageal motility disorders like achalasia.
Not a fit: Patients without swallowing difficulties or acid reflux would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to more precise diagnoses and more effective treatments for patients suffering from swallowing difficulties and acid reflux.
How similar studies have performed: The 'Chicago Classification' has already shown success in standardizing diagnoses, and this project builds upon that established framework with novel approaches.
Where this research is happening
Chicago, United States
- Northwestern University — Chicago, United States (Active)
Researchers
- Principal investigator: Pandolfino, John E — Northwestern University
- Study coordinator: Pandolfino, John E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.