Improving how we track breast cancer chemotherapy with 3D imaging
Monitoring neoadjuvant chemotherapy of breast cancer using 3D subharmonic aided pressure estimation
This project aims to develop a new 3D ultrasound method to see how well chemotherapy is working for breast cancer patients before surgery.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11160431 on NIH RePORTER |
What this research studies
For patients with breast cancer, chemotherapy is often given before surgery to shrink tumors. This project is developing a new way to monitor these treatments using a special 3D ultrasound technique. This advanced imaging method measures changes in tumor stiffness, which can tell doctors if the chemotherapy is effectively shrinking the cancer. By getting a clearer picture of treatment response earlier, doctors can make more informed decisions about a patient's care.
Who could benefit from this research
Good fit: Patients undergoing neoadjuvant chemotherapy for breast cancer who might benefit from more precise monitoring of their treatment response would be ideal candidates.
Not a fit: Patients who are not receiving neoadjuvant chemotherapy for breast cancer or those with other cancer types would likely not receive direct benefit from this specific imaging technique.
Why it matters
Potential benefit: If successful, this new imaging technique could help doctors better understand how breast cancer chemotherapy is working, potentially leading to more personalized and effective treatment plans.
How similar studies have performed: While ultrasound is a common imaging tool, this specific 3D subharmonic aided pressure estimation technique for monitoring neoadjuvant chemotherapy in breast cancer appears to be a novel application.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Nam, Kibo — Thomas Jefferson University
- Study coordinator: Nam, Kibo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.