Improving how we test for infections in children on ventilators
Optimizing Respiratory Culture Practices for Mechanically Ventilated Children
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10983343
This study is looking at how to improve the way doctors use tests to check for lung infections in children on ventilators, with the hope of finding better methods that help kids get the right treatment while also reducing the use of unnecessary antibiotics.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10983343 on ClinicalTrials.gov |
What this research studies
This research focuses on optimizing the practices surrounding endotracheal aspirate cultures (EACs) used to diagnose ventilator-associated infections (VAIs) in mechanically ventilated children. It aims to define current EAC practices across the country and identify the best methods for using these tests effectively. By implementing a pilot program to improve EAC practices, the research will assess clinical outcomes and explore the challenges and facilitators of adopting better diagnostic stewardship. The ultimate goal is to reduce unnecessary antibiotic use, which can lead to antibiotic resistance and other complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are mechanically ventilated and suspected of having ventilator-associated infections.
Not a fit: Patients who are not mechanically ventilated or who do not have suspected ventilator-associated infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic practices that reduce unnecessary antibiotic treatments and improve health outcomes for ventilated children.
How similar studies have performed: Previous research has shown that optimizing diagnostic practices can significantly improve patient outcomes and reduce antibiotic misuse, indicating that this approach has potential for success.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SICK-SAMUELS, ANNA — JOHNS HOPKINS UNIVERSITY
- Study coordinator: SICK-SAMUELS, ANNA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Airway infections