Improving how we see cells and tissues using advanced microscopy techniques.
Imaging Cells and Tissues with Super-Resolution Structured Illumination Microscopy
This study is working on improving a special type of microscope that helps scientists see tiny parts of cells more clearly, which could help us understand how cells work and interact better.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Colorado Springs, United States) |
| Project ID | NIH-10796461 on NIH RePORTER |
What this research studies
This research focuses on enhancing the resolution of fluorescence microscopy, a key tool for studying biological systems at the cellular level. The project aims to develop super-resolution structured illumination microscopy (SIM) techniques that can visualize cellular structures smaller than the current resolution limit of 250 nm. By innovating both the optical design and data processing methods, the researchers hope to enable clearer imaging of cells and tissues, which has been challenging with existing methods. This work could lead to better understanding of cellular functions and interactions.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include patients with conditions that involve cellular abnormalities, such as cancer or genetic disorders.
Not a fit: Patients with conditions unrelated to cellular structure or function may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with improved diagnostic tools and treatments by allowing scientists to better understand cellular processes.
How similar studies have performed: Other research has shown success with super-resolution microscopy techniques, indicating a promising potential for this approach.
Where this research is happening
Colorado Springs, United States
- University of Colorado — Colorado Springs, United States (Active)
Researchers
- Principal investigator: Hagen, Guy — University of Colorado
- Study coordinator: Hagen, Guy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.