Improving how we measure symptoms for nephrotic syndrome

Preparing a clinical outcomes assessment set for nephrotic syndrome [Prepare-NS]

NIH-funded research University of Michigan at Ann Arbor · NIH-11082524

This project aims to create better ways to measure how patients with nephrotic syndrome experience symptoms like fluid overload, making it easier to understand how new treatments are working.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11082524 on NIH RePORTER

What this research studies

We are working to develop and test a core set of tools to measure important symptoms for people with nephrotic syndrome, especially focusing on fluid overload. This involves gathering insights from patients, doctors, regulators, and drug developers to make sure these tools truly reflect what matters most to patients. Our goal is to create reliable and patient-focused ways to track symptoms, which will help in the development of new medicines. Once developed, these new measurement tools will be made widely available for use in future clinical trials.

Who could benefit from this research

Good fit: Patients with nephrotic syndrome, particularly those experiencing fluid overload, may be ideal candidates for providing input on their experiences and symptoms.

Not a fit: Patients who do not have nephrotic syndrome or are not experiencing fluid overload would likely not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to more accurate and patient-centered ways to measure treatment effectiveness for nephrotic syndrome, potentially speeding up the development of new therapies.

How similar studies have performed: While the development of clinical outcome assessments is an established field, this specific effort to create a core set for nephrotic syndrome with a focus on fluid overload is a novel and comprehensive approach.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.