Improving how we conduct studies for opioid use disorder treatments
Leveraging harmonized data to improve external validity and efficiency of clinical trials for treating opioid use disorder
This project aims to make future studies on opioid use disorder treatments more effective and efficient by combining information from many past studies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11164767 on NIH RePORTER |
What this research studies
We know that conducting studies for conditions like opioid use disorder can be challenging, often making it hard to find treatments that work for everyone. This project focuses on a new way to combine patient data from different studies, which helps us understand if treatments work for a larger group of people and if certain treatments are better for specific individuals. By doing this, we hope to move away from a 'one-size-fits-all' approach and find more personalized care strategies. This method helps us learn more from existing information, making future treatment discoveries faster and more tailored.
Who could benefit from this research
Good fit: This project focuses on improving the design of future clinical studies for opioid use disorder, so it does not directly involve patient participation at this stage.
Not a fit: Patients not currently seeking or participating in opioid use disorder treatment studies would not directly benefit from this specific research on trial methodology.
Why it matters
Potential benefit: If successful, this work could lead to more effective and personalized treatments for opioid use disorder by improving how future clinical studies are designed and analyzed.
How similar studies have performed: The statistical methods for combining data from different studies are relatively new, and this project aims to address remaining challenges in this area.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Miles, Caleb Hilliard — Columbia University Health Sciences
- Study coordinator: Miles, Caleb Hilliard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.