Improving how we assess side effects and patient experiences in cancer treatments
Advancing Analysis and Interpretation ofAdverse Events and PROs in Cancer Clinical Trials
This study is looking at how cancer treatments, especially immunotherapy, affect patients by gathering their experiences and side effects, so we can better understand and improve their care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10477392 on NIH RePORTER |
What this research studies
This research focuses on developing new methods to analyze and present data related to the side effects and patient-reported outcomes of cancer treatments, particularly immunotherapy. By collaborating with the NRG Oncology Statistical Center, the team will utilize data from clinical trials to create a toxicity index that captures the overall experience of patients regarding treatment tolerability. This approach aims to enhance the understanding of how different treatments affect patients and to identify predictors of treatment-related toxicity, ultimately improving patient care and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing immunotherapy, particularly those in early metastatic disease or adjuvant therapy settings.
Not a fit: Patients not undergoing immunotherapy or those with advanced-stage cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better assessment of treatment side effects, helping to tailor cancer therapies to individual patient needs.
How similar studies have performed: Previous research has shown promise in using patient-reported outcomes to assess treatment tolerability, indicating that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Tighiouart, Mourad — Cedars-Sinai Medical Center
- Study coordinator: Tighiouart, Mourad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.