Improving how we assess side effects and patient experiences in breast cancer treatments
Advancing Analysis and Interpretation of Adverse Events and PROs in Cancer Clinical Trials
This study is working to improve how we understand and share the side effects that breast cancer patients experience during treatment, so that future therapies can be better tailored to meet their needs.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10884827 on NIH RePORTER |
What this research studies
This research focuses on enhancing the analysis of side effects and patient-reported outcomes in breast cancer clinical trials. By collaborating with the NRG Oncology Statistical Center, the team aims to develop new methods for evaluating treatment tolerability and presenting data more effectively. They will utilize data from previous clinical trials to create a toxicity index that better captures the overall experience of patients undergoing immunotherapy and other treatments. This approach seeks to provide a more nuanced understanding of treatment-related side effects, which can inform better decision-making for future therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are breast cancer patients undergoing immunotherapy or other treatments who are willing to report their experiences and side effects.
Not a fit: Patients who are not undergoing treatment for breast cancer or those who do not wish to participate in reporting their treatment experiences may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved assessment of treatment side effects, ultimately enhancing patient care and treatment options for breast cancer.
How similar studies have performed: Previous research has shown success in using patient-reported outcomes to assess treatment tolerability, making this approach both innovative and grounded in established methodologies.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Tighiouart, Mourad — Cedars-Sinai Medical Center
- Study coordinator: Tighiouart, Mourad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.