Improving How the Small Intestine Handles Excess Sugar
Official title: Numerical Experimentation of the Therapeutic Effect of Excess Glucose Transglycosylation and Optimization in the Proximal Small Intestine.
Funded at Prairie View Agri & Mech University · NIH-11145802 · Data updated 2026-11-12
This project aims to find the best way to help the small intestine manage excess sugar, which could benefit people with adult-onset diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Prairie View Agri & Mech University NIH-funded |
| Lab location | 1 site (Prairie View, UNITED STATES) |
| Project start | August 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $175,935 |
| NIH project number | 5R16GM154691-02 |
| Project ID | NIH-11145802 on NIH RePORTER |
Who could benefit from this research
✓Could help
This foundational research is for anyone interested in how the body processes sugar and how new approaches might help manage adult-onset diabetes.
✕Less likely to help
Patients seeking immediate treatment options would not directly benefit from this early-stage, computational modeling research.
What this research studies
Our digestive system works hard to process nutrients and keep our bodies balanced. When there's too much sugar like glucose or fructose, it can put a strain on organs like the liver and contribute to conditions such as adult-onset diabetes. This research uses computer modeling to figure out the most effective ways to remove excess sugar from the upper part of the small intestine. By understanding these processes better, we hope to develop new strategies to help the body maintain healthy sugar levels.
Why it matters
Potential benefit: If successful, this work could lead to new ways to help people with adult-onset diabetes better manage their blood sugar levels and reduce the risk of related liver problems.
How similar studies have gone: This project explores a novel computational approach to optimize sugar remediation in the small intestine, building on existing knowledge of gastrointestinal physiology.
Where this research is happening
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Prairie View Agri & Mech University
Prairie View, United States Active
Researchers
- Principal investigator: Olanrewaju, Kazeem — Prairie View Agri & Mech University
- Study coordinator: Olanrewaju, Kazeem
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.