Improving how medicines and materials work in the body using fluorine

Understanding and controlling the cellular fate of fluorine-modified biologics

NIH-funded research Pennsylvania State University, the · NIH-11125940

This research explores how adding fluorine to biological molecules can help us create better medicines and materials for the body.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-11125940 on NIH RePORTER

What this research studies

Our bodies use many natural building blocks like proteins and DNA. This project looks at how adding a special element called fluorine to these building blocks can change how they behave. We want to understand these changes better, especially how fluorine affects how proteins and DNA interact within our cells and tissues. This knowledge could help us design new and improved medical materials or even better ways to deliver medicines in the future.

Who could benefit from this research

Good fit: This foundational research does not directly involve patient participation at this stage.

Not a fit: Patients will not receive direct medical benefit from participating in this fundamental laboratory research.

Why it matters

Potential benefit: If successful, this work could lead to the development of new, more effective medicines and medical materials that interact precisely with our bodies.

How similar studies have performed: This project builds upon recent discoveries by the principal investigator's lab, exploring new ways that fluorine interacts with biological molecules.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.