Improving how lung cancer screening nodules are evaluated

Optimizing Lung Cancer Screening Nodule Evaluation

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10890080

This study is looking to improve how doctors manage small spots on the lungs found during lung cancer screenings, helping to avoid unnecessary tests for patients while still catching any cancer early when it’s easier to treat.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10890080 on NIH RePORTER

What this research studies

This research aims to enhance the management of pulmonary nodules detected during lung cancer screenings, which are often found through low-dose computed tomography (LDCT). Given that a significant number of these nodules are benign, the study will develop an optimal management algorithm that considers various patient factors such as age, sex, smoking history, and comorbidities. By refining follow-up procedures and reducing unnecessary invasive tests, the research seeks to minimize patient harm while ensuring early detection of lung cancer when it is most treatable.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have undergone lung cancer screening and have been found to have pulmonary nodules.

Not a fit: Patients who do not have pulmonary nodules detected during lung cancer screening may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective lung cancer screening practices, ultimately improving patient outcomes.

How similar studies have performed: Previous research has shown that optimizing management strategies for cancer screening can lead to significant improvements in patient care, indicating that this approach has potential for success.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer ControlCancer Control ScienceCancer EtiologyCancer Intervention and Surveillance Modeling Network
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.