Improving how inhaled medications and vaccines work in the lungs
Breathing, Full Volume Pulmonary Deposition Model to Transform Development of Aerosol Therapeutics
This study is working on a new tool to help understand how inhaled medications and vaccines work in the lungs, so that people with breathing problems can get better treatments tailored to their unique breathing patterns.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Delaware NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11121583 on NIH RePORTER |
What this research studies
This research focuses on developing a new model to better predict how inhaled medications and vaccines will behave in the lungs. It addresses the challenges posed by the complex structure and motion of airways, which can affect how well these treatments work. By creating a dynamic preclinical tool called the TIDAL model, researchers aim to measure how aerosols deposit in the lungs based on individual breathing patterns and anatomy. This could lead to more effective inhalation therapies for various respiratory diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who may benefit from inhaled therapies for respiratory conditions.
Not a fit: Patients with non-respiratory conditions or those under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective inhaled treatments and vaccines for respiratory diseases.
How similar studies have performed: While the approach is innovative, similar research has shown promise in improving inhalation therapies, indicating potential for success.
Where this research is happening
Newark, UNITED STATES
- University of Delaware — Newark, United States (Active)
Researchers
- Principal investigator: Fromen, Catherine a — University of Delaware
- Study coordinator: Fromen, Catherine a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.