Improving how biological sex is considered in medical research

SCISIPBIO: Maximizing rigor and reproducibility when considering Sex as a Biological Variable in research

NIH-funded research Emory University · NIH-10898922

This study is looking at how including biological sex in medical research can make treatments better for everyone, and it’s designed for researchers who want to improve their studies and ensure they work well for all genders.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10898922 on NIH RePORTER

What this research studies

This research focuses on enhancing the rigor and reproducibility of medical studies by ensuring that biological sex is properly considered in research designs. It aims to analyze how sex-specific data is reported and to identify common pitfalls in the analytical approaches used by researchers. By employing a mixed-method approach, the project will develop tools and guidelines to improve the evaluation of studies that incorporate sex as a biological variable. This work is crucial for advancing precision medicine and ensuring that treatments are effective for all genders.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals participating in clinical studies where sex-based differences in treatment responses are relevant.

Not a fit: Patients who are not involved in clinical research or those whose conditions do not exhibit sex-based differences may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized medical treatments that take into account the differences between sexes.

How similar studies have performed: Previous research has shown that improving the consideration of sex as a biological variable can lead to better health outcomes, indicating that this approach has potential for success.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.