Improving how antibodies attach to gold nanoparticles for better diagnostics
Official title: Enzyme-Mediated Site-Specific Conjugation of Antibodies to Nanoparticles
Funded at Illinois State University · NIH-10436681 · Data updated 2026-11-12
This study is working on a new way to attach antibodies to tiny gold particles to make medical tests more reliable and effective, which could help doctors detect different health conditions more accurately.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Illinois State University NIH-funded |
| Lab location | 1 site (Normal, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $369,921 |
| NIH project number | 1R15GM146167-01 |
| Project ID | NIH-10436681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research include those requiring advanced diagnostic testing for various medical conditions.
✕Less likely to help
Patients who are not undergoing diagnostic testing or do not require antibody-based diagnostics may not benefit from this research.
What this research studies
This research focuses on enhancing the way antibodies are connected to gold nanoparticles, which are tiny particles that can be used in medical diagnostics. The team aims to develop a method that allows for a more stable and effective attachment of antibodies to these nanoparticles, ensuring that they maintain their activity and orientation. By using enzyme-mediated techniques, the researchers hope to create highly active and stable antibody-gold nanoparticle conjugates that can improve diagnostic tests. This work could lead to better detection methods for various medical conditions.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable diagnostic tests for patients.
How similar studies have gone: Previous research has shown promise in improving antibody conjugation techniques, suggesting that this approach could lead to significant advancements in diagnostic methods.
Where this research is happening
-
Illinois State University
Normal, United States Active
Researchers
- Principal investigator: Driskell, Jeremy D. — Illinois State University
- Study coordinator: Driskell, Jeremy D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.