Improving how Alzheimer's disease is diagnosed using MRI and predictive modeling
Official title: Advancing Alzheimer's Diagnosis: MRI-Based Predictive Modeling of Alzheimer’s Disease Molecular Subtypes
Funded at Upstate Medical University · NIH-10998834 · Data updated 2026-11-12
This study is looking to improve how we diagnose Alzheimer's disease by using advanced brain scans and genetic information to find different types of the disease, so if you join, you might help us figure out how to catch it earlier and plan better treatments!
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Upstate Medical University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $53,974 |
| NIH project number | 1F30AG090044-01 |
| Project ID | NIH-10998834 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals showing early signs of cognitive decline or those diagnosed with Alzheimer's disease.
✕Less likely to help
Patients with other forms of dementia or cognitive impairment unrelated to Alzheimer's disease may not benefit from this research.
What this research studies
This research aims to enhance the diagnosis of Alzheimer's disease (AD) by using advanced MRI techniques and predictive modeling to identify different molecular subtypes of the disease. By analyzing genetic, epigenetic, and neuroimaging data from the same individuals, the study seeks to uncover biological signatures that differentiate these subtypes. This approach could lead to earlier and more accurate diagnoses, which is crucial for effective treatment planning. Patients participating in this research may undergo MRI scans and provide biological samples to help develop these predictive models.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of Alzheimer's disease, allowing for timely interventions and personalized treatment strategies.
How similar studies have gone: Previous research has shown promise in using neuroimaging techniques for diagnosing Alzheimer's disease, indicating that this approach could yield significant advancements.
Where this research is happening
-
Upstate Medical University
Syracuse, United States Active
Researchers
- Principal investigator: Mikhailova, Tatiana — Upstate Medical University
- Study coordinator: Mikhailova, Tatiana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.