Improving how aging individuals process vocal communication signals
Epigenetic rescue of age-related deficits in auditory processing of vocal communication signals
This study is looking at how getting older affects our ability to understand and remember sounds, like voices, and it’s using songbirds to help find ways to boost memory for these sounds, which could lead to better communication skills for older adults.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Queens College NIH-funded |
| Lab location | 1 site (Flushing, United States) |
| Project ID | NIH-10730818 on NIH RePORTER |
What this research studies
This research investigates how age-related cognitive decline affects the ability to process and remember vocal communication signals. By using a songbird model, which learns vocal signals similarly to humans, the study aims to explore targeted epigenetic manipulation to enhance auditory memory. The researchers will also look at how this manipulation impacts inflammation and neurogenesis in the brain areas responsible for auditory processing. This approach could provide insights into potential interventions for improving communication abilities in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing age-related auditory processing deficits.
Not a fit: Patients who are not experiencing age-related cognitive decline or auditory processing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance auditory processing and memory in aging individuals, potentially reducing social isolation and associated mental health issues.
How similar studies have performed: While the use of songbirds for studying auditory processing is well-established, the specific approach of epigenetic manipulation in the context of aging is relatively novel and has not been extensively tested.
Where this research is happening
Flushing, United States
- Queens College — Flushing, United States (Active)
Researchers
- Principal investigator: Pytte, Carolyn Liv — Queens College
- Study coordinator: Pytte, Carolyn Liv
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.