Improving hospital incident reporting to enhance patient safety

A Cluster Randomized Controlled Trial Comparing the Safety Action Feedback and Engagement (SAFE) Loop with an Established Incident Reporting System

NIH-funded research Cedars-Sinai Medical Center · NIH-10881891

This study is testing a new way to help nurses report medication safety issues in hospitals better, so they can get feedback and improve patient safety, and it’s comparing this new method to the current system to see which one works best.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10881891 on NIH RePORTER

What this research studies

This research investigates a new approach called the Safety Action Feedback and Engagement (SAFE) Loop, which aims to improve the effectiveness of incident reporting systems in hospitals. By focusing on high-priority medication safety problems, the SAFE Loop encourages nurses to report incidents more effectively and provides them with feedback on the issues identified. The study will compare the SAFE Loop with an existing incident reporting system to determine which is more effective in enhancing patient safety. The methodology includes gathering input from nurses, training them on reporting, and integrating various sources of information to create actionable insights.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients receiving care in hospitals where the SAFE Loop is implemented and those affected by medication errors.

Not a fit: Patients who are not currently hospitalized or those receiving care in facilities not participating in the SAFE Loop may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a significant reduction in medication errors and improve overall patient safety in hospitals.

How similar studies have performed: Previous research in other high-risk industries has shown that improved incident reporting can enhance safety outcomes, suggesting potential success for this novel approach in healthcare.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.