Improving hospital care for people with sickle cell disease
Official title: Formative Implementation Research on Translating Evidence to Hospital Care for People Living With Sickle Cell Disease (FIRES)
Funded at University of Rochester · NIH-10939137 · Data updated 2026-11-12
This study is all about making hospital visits better for people with sickle cell disease by creating personalized care plans to help manage pain quickly and effectively, so you can feel more comfortable and get the treatment you need without delays.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $191,792 |
| NIH project number | 1K23HL174588-01 |
| Project ID | NIH-10939137 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older who are living with sickle cell disease and experience acute vaso-occlusive episodes.
✕Less likely to help
Patients who do not have sickle cell disease or are not experiencing acute pain episodes may not benefit from this research.
What this research studies
This research focuses on enhancing the hospital care experience for individuals living with sickle cell disease (SCD) by developing and implementing individualized care plans for acute pain episodes. The project aims to address barriers such as clinician knowledge gaps, stigma, and systemic complexities that often lead to delays in treatment. By engaging patients in the process, the research seeks to create protocols that improve pain management and overall care during hospital stays. The goal is to ensure that patients receive timely and effective treatment, ultimately reducing the risk of severe complications and death.
Why it matters
Potential benefit: If successful, this research could lead to better pain management and improved hospital experiences for patients with sickle cell disease.
How similar studies have gone: Previous research has shown that individualized care plans can improve patient experiences in emergency settings, indicating potential for success in inpatient care as well.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Jenkins, Ashley — University of Rochester
- Study coordinator: Jenkins, Ashley
Related research
Other NIH-funded projects on the same topics.
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Digital twins of the spleen to help design better therapies for sickle cell disease
A computer-driven replica of the spleen is being developed to speed up creating safer and more effective treatments for people with sickle cell disease.
-
Accelerating hydroxyurea use for sickle cell disease in Nigeria
A pragmatic study in Nigeria aims to help doctors use hydroxyurea more consistently for people with sickle cell disease.
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Immune and nerve signals behind acupuncture relief for sickle cell pain
This NIH grant explores how acupuncture helps reduce pain and opioid use for people with sickle cell disease.
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Mindfulness-based Support for Pain and Sleep in Young People with Sickle Cell Disease
A digital mindfulness program is being tailored for adolescents and young adults with sickle cell disease to help with pain and sleep and is being tested for practicality and early effectiveness.
-
How diet affects white blood cells and sickle cell disease
A study looks at how nutrition, from early life to adulthood, influences sickle cell disease by examining neutrophils and disease severity in people with SCD and in a mouse model.
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Nutrition-based plan to ease pain in sickle cell disease
A nutrition-based approach is being tested to reduce pain for people living with sickle cell disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.