Improving home ventilation for children with chronic lung disease
Official title: HOMeVent4Kids: Home-based Optimization of Mechanical Ventilation for Children
Funded at Lurie Children's Hospital of Chicago · NIH-10902008 · Data updated 2026-11-12
This study is looking at ways to help kids with chronic lung disease who use home ventilation, by figuring out how long they need it and finding safe ways to reduce that time, all while listening to families and healthcare providers to make their care better and easier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 5, 2020 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $132,192 |
| NIH project number | 5K23HL149829-05 |
| Project ID | NIH-10902008 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years with chronic lung disease who are currently dependent on home mechanical ventilation.
✕Less likely to help
Patients who do not have chronic lung disease or who are not on home mechanical ventilation may not benefit from this research.
What this research studies
This research focuses on enhancing the care of children with chronic lung disease who need home mechanical ventilation. The project aims to identify factors that influence how long these children require ventilation and to develop strategies for safely reducing this duration. By integrating insights from patients, families, and healthcare services, the research seeks to create a more effective management plan for these children. The ultimate goal is to alleviate the burden on families and improve health outcomes for young patients.
Why it matters
Potential benefit: If successful, this research could lead to safer and more efficient management of home mechanical ventilation, improving the quality of life for children and their families.
How similar studies have gone: Previous research has shown promise in optimizing care for children with chronic conditions, suggesting that this approach could yield beneficial results.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Foster, Carolyn C. — Lurie Children's Hospital of Chicago
- Study coordinator: Foster, Carolyn C.
Related research
Other NIH-funded projects on the same topics.
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Advancing Acute Respiratory Infection Care for Kids on Home Ventilators
This grant aims to improve how doctors and families manage acute respiratory infections in children who rely on invasive long-term home ventilation.
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A Tablet-Based Emotion Regulation Program for Surrogate Decision-Makers of ICU Patients on Ventilation
A randomized trial tests a brief tablet program to help people who decide for ICU patients on ventilation feel less anxious and make better decisions.
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Optimizing pain relief for children on mechanical ventilation
A large, multi-site trial tests whether adding non-opioid pain medicines to standard opioid care can reduce pain and lower opioid use in children on breathing machines in PICUs.
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Role of titin in diaphragm weakness during mechanical ventilation
This grant studies how the diaphragm’s core proteins work together, especially titin and myosin, to understand why diaphragm weakness happens during mechanical ventilation.
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Time-limited trials to guide invasive ventilation decisions
A scientific team is testing how short, structured trials of life-support in ICU patients with acute respiratory failure can help patients and families choose the best path.
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How breathing machines can harm the kidneys
Doctors will look at how ventilators change kidney filtering and salt handling in people who are critically ill to help prevent kidney damage.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.