Improving home administration of long-acting HIV treatments

RFA-PS-23-004, Innovative Administration of Long-Acting Injectables for HIV Treatment Enhancement at Home (INVITE-Home)

NIH-funded research University of California, San Francisco · NIH-10917000

This study is looking at a new way for people living with HIV to get their long-acting injections at home, by having family or friends trained to give them, making it easier and more comfortable for everyone involved.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10917000 on NIH RePORTER

What this research studies

This research explores a new approach to administering long-acting injectable antiretroviral therapy (LAI-ART) for people living with HIV (PWH) in the comfort of their homes. By training laypersons, such as family members or friends, to administer these injections, the study aims to reduce the stigma and logistical challenges associated with frequent clinic visits. The goal is to enhance patient engagement and adherence to treatment while addressing barriers that prevent effective HIV care. This innovative model has shown promise in other healthcare contexts but is being evaluated specifically for HIV treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are interested in long-acting injectable treatments and have supportive family members or friends willing to be trained as injectors.

Not a fit: Patients who are not living with HIV or those who prefer traditional clinic-based treatment methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve access to HIV treatment and enhance the quality of life for patients by allowing them to receive care in a more private and convenient setting.

How similar studies have performed: Similar approaches in other healthcare contexts have shown success, indicating potential for positive outcomes in this novel application for HIV treatment.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.