NIH-funded research U01 cooperative agreement

Improving home administration of long-acting HIV treatments

Official title: RFA-PS-23-004, Innovative Administration of Long-Acting Injectables for HIV Treatment Enhancement at Home (INVITE-Home)

Funded at University of California, San Francisco · NIH-10917000 · Data updated 2026-11-12

This study is looking at a new way for people living with HIV to get their long-acting injections at home, by having family or friends trained to give them, making it easier and more comfortable for everyone involved.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startSeptember 30, 2023
Project endSeptember 29, 2027
Funding year2024
Award (this year)$1,000,000
NIH project number5U01PS005259-02
Project IDNIH-10917000 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living with HIV who are interested in long-acting injectable treatments and have supportive family members or friends willing to be trained as injectors.

Less likely to help

Patients who are not living with HIV or those who prefer traditional clinic-based treatment methods may not benefit from this research.

What this research studies

This research explores a new approach to administering long-acting injectable antiretroviral therapy (LAI-ART) for people living with HIV (PWH) in the comfort of their homes. By training laypersons, such as family members or friends, to administer these injections, the study aims to reduce the stigma and logistical challenges associated with frequent clinic visits. The goal is to enhance patient engagement and adherence to treatment while addressing barriers that prevent effective HIV care. This innovative model has shown promise in other healthcare contexts but is being evaluated specifically for HIV treatment.

Why it matters

Potential benefit: If successful, this research could significantly improve access to HIV treatment and enhance the quality of life for patients by allowing them to receive care in a more private and convenient setting.

How similar studies have gone: Similar approaches in other healthcare contexts have shown success, indicating potential for positive outcomes in this novel application for HIV treatment.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Saberi, Parya — University of California, San Francisco
  • Study coordinator: Saberi, Parya

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.