Improving HIV treatment strategies in South Africa
Official title: Evaluating UTT with a National HIV Cohort to Optimize South Africa's HIV Response (ENCORE)
Funded at Wits Health Consortium (Pty), LTD · NIH-10839467 · Data updated 2026-11-12
This study is looking at how well starting HIV treatment right away helps patients in South Africa stay on track with their care, so we can learn what works best and make things better for everyone living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wits Health Consortium (Pty), LTD NIH-funded |
| Lab location | 1 site (Parktown, South Africa) |
| Project start | May 15, 2020 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $298,871 |
| NIH project number | 5R01AI152149-05 |
| Project ID | NIH-10839467 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with HIV in South Africa who are starting treatment or are currently receiving care.
✕Less likely to help
Patients who are not diagnosed with HIV or those who are not receiving treatment in South Africa may not benefit from this research.
What this research studies
This research investigates the effectiveness of the Universal Test-and-Treat (UTT) approach in South Africa, which aims to start HIV patients on treatment immediately upon diagnosis. By analyzing a large national HIV cohort, the study seeks to understand how many patients successfully engage with treatment and where they may drop out of care. The research will utilize comprehensive laboratory records and patient data to track treatment outcomes over time, providing insights into real-world challenges faced by patients. This information will help refine HIV treatment policies and improve patient care in the country.
Why it matters
Potential benefit: If successful, this research could lead to improved HIV treatment strategies that enhance patient retention and health outcomes.
How similar studies have gone: Previous research has shown promising results with similar UTT approaches in clinical trials, indicating potential for real-world effectiveness.
Where this research is happening
-
Wits Health Consortium (Pty), LTD
Parktown, South Africa Active
Researchers
- Principal investigator: Onoya, Dorina — Wits Health Consortium (Pty), LTD
- Study coordinator: Onoya, Dorina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.