Improving HIV treatment strategies in South Africa

Evaluating UTT with a National HIV Cohort to Optimize South Africa's HIV Response (ENCORE)

NIH-funded research Wits Health Consortium (Pty), LTD · NIH-10839467

This study is looking at how well starting HIV treatment right away helps patients in South Africa stay on track with their care, so we can learn what works best and make things better for everyone living with HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWits Health Consortium (Pty), LTD NIH-funded
Lab location1 site (Parktown, South Africa)
Project IDNIH-10839467 on NIH RePORTER

What this research studies

This research investigates the effectiveness of the Universal Test-and-Treat (UTT) approach in South Africa, which aims to start HIV patients on treatment immediately upon diagnosis. By analyzing a large national HIV cohort, the study seeks to understand how many patients successfully engage with treatment and where they may drop out of care. The research will utilize comprehensive laboratory records and patient data to track treatment outcomes over time, providing insights into real-world challenges faced by patients. This information will help refine HIV treatment policies and improve patient care in the country.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with HIV in South Africa who are starting treatment or are currently receiving care.

Not a fit: Patients who are not diagnosed with HIV or those who are not receiving treatment in South Africa may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved HIV treatment strategies that enhance patient retention and health outcomes.

How similar studies have performed: Previous research has shown promising results with similar UTT approaches in clinical trials, indicating potential for real-world effectiveness.

Where this research is happening

Parktown, South Africa

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.