Improving HIV treatment for people with opioid use disorder in Malaysia

Implementation of Seek, Test, Treat & Retain Strategies among People Who Inject Drugs in Malaysia

['FUNDING_R01'] · YALE UNIVERSITY · NIH-10453749

This study is looking to help people in Malaysia who have HIV and also struggle with opioid use by trying out a new treatment approach that combines HIV medication with methadone, to see if it helps more patients stick to their treatment and stay healthier.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-10453749 on ClinicalTrials.gov

What this research studies

This research aims to enhance the treatment outcomes for individuals living with HIV who also struggle with opioid use disorder in Malaysia. By implementing a new care model across four large regional HIV/AIDS treatment centers, the study will evaluate how effectively this model can increase the number of patients receiving antiretroviral therapy (ART) and improve their adherence to treatment. Participants will be enrolled to receive both ART and methadone maintenance treatment, with their health outcomes compared to those receiving standard care. The study will identify barriers and facilitators to implementing this improved care model, ultimately aiming to reduce mortality and HIV incidence in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who also have an opioid use disorder and are seeking treatment in Malaysia.

Not a fit: Patients who do not have HIV or opioid use disorder may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve health outcomes for patients by increasing access to effective HIV treatment and support for opioid use disorder.

How similar studies have performed: Previous research has shown that integrated treatment approaches for HIV and substance use disorders can lead to improved patient outcomes, indicating potential success for this study's approach.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.