Improving HIV treatment for patients in Malawi who have interrupted their care
Official title: Ongoing Dynamic Choice to Address HIV Treatment Interruption in Malawi (CHOICE)
Funded at University of California Los Angeles · NIH-11087380 · Data updated 2026-11-12
This study is looking to help people in Malawi who have had trouble sticking to their HIV treatment by offering them personalized support and choices about how and where they get their medication, all while providing ongoing counseling for two years.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | April 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $653,677 |
| NIH project number | 1R01MH139452-01 |
| Project ID | NIH-11087380 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals in Malawi who have experienced treatment interruptions for HIV for more than 28 days.
✕Less likely to help
Patients who have never interrupted their HIV treatment or those who are not residing in Malawi may not benefit from this research.
What this research studies
This research focuses on addressing the challenges faced by individuals in Malawi who have experienced interruptions in their HIV treatment. It aims to provide personalized, long-term support tailored to the unique needs of these patients, allowing them to choose how they receive their antiretroviral therapy (ART). Through a cluster randomized control trial, participants will receive ongoing counseling and the flexibility to adjust their treatment options, including the frequency and location of ART delivery. This approach is designed to enhance patient engagement and improve health outcomes over a 24-month period.
Why it matters
Potential benefit: If successful, this research could lead to improved viral suppression rates and better overall health for patients who struggle with maintaining consistent HIV treatment.
How similar studies have gone: Previous research has shown that personalized and flexible treatment approaches can significantly improve health outcomes for patients with chronic conditions, suggesting potential success for this novel intervention.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Dovel, Kathryn L — University of California Los Angeles
- Study coordinator: Dovel, Kathryn L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.