Improving HIV treatment for patients in Malawi who have interrupted their care

Ongoing Dynamic Choice to Address HIV Treatment Interruption in Malawi (CHOICE)

NIH-funded research University of California Los Angeles · NIH-11087380

This study is looking to help people in Malawi who have had trouble sticking to their HIV treatment by offering them personalized support and choices about how and where they get their medication, all while providing ongoing counseling for two years.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11087380 on NIH RePORTER

What this research studies

This research focuses on addressing the challenges faced by individuals in Malawi who have experienced interruptions in their HIV treatment. It aims to provide personalized, long-term support tailored to the unique needs of these patients, allowing them to choose how they receive their antiretroviral therapy (ART). Through a cluster randomized control trial, participants will receive ongoing counseling and the flexibility to adjust their treatment options, including the frequency and location of ART delivery. This approach is designed to enhance patient engagement and improve health outcomes over a 24-month period.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals in Malawi who have experienced treatment interruptions for HIV for more than 28 days.

Not a fit: Patients who have never interrupted their HIV treatment or those who are not residing in Malawi may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved viral suppression rates and better overall health for patients who struggle with maintaining consistent HIV treatment.

How similar studies have performed: Previous research has shown that personalized and flexible treatment approaches can significantly improve health outcomes for patients with chronic conditions, suggesting potential success for this novel intervention.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.