Improving HIV treatment and retention for people who inject drugs

PWID Opportunities to Improve TrEat and Retain (POINTER)

NIH-funded research Johns Hopkins University · NIH-11378866

This program tests combining same-day HIV treatment, community-based care, and personal support to help people who inject drugs start and stay on HIV medication.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11378866 on NIH RePORTER

What this research studies

You may be reached through community networks to find people who inject drugs who are HIV-positive or out of care. The project randomly assigns people to receive same-day antiretroviral therapy (ART), community-based clinical care, and/or psychosocial navigation support in different combinations. By comparing these groups, the team will learn which single or combined approaches help people start treatment quickly and stay on it. The goal is to improve retention in care and viral suppression among people who inject drugs in affected regions of India.

Who could benefit from this research

Good fit: People who inject drugs in the trial locations who are HIV-positive, including those unaware of their diagnosis or currently out of care, are the intended participants.

Not a fit: People who are HIV-negative, do not inject drugs, or live outside the trial regions in India are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could help more people who inject drugs begin HIV treatment right away and remain on therapy, lowering illness and transmission risk.

How similar studies have performed: Components like same-day ART and community-based support have improved outcomes in other HIV programs, but combining these approaches specifically for people who inject drugs in India is relatively new.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.