Improving HIV treatment and prevention for adolescents in South Africa
Adolescent-tailored HIV treatment and prevention strategies in South Africa: projecting clinical benefits and value (Supplement)
This study is looking at how well long-acting injectable HIV treatments work for teens and young adults in Cape Town, South Africa, to see if they can help them stick to their medication better and stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11126303 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of long-acting injectable antiretroviral therapy (LAI ART) for adolescents and young adults living with HIV in Cape Town, South Africa. It aims to understand how this treatment can improve adherence and reduce the risk of virologic failure, particularly in a population that has struggled with traditional oral therapies. By analyzing data on drug effectiveness and patient adherence, the study will use computer simulations to project the clinical and economic benefits of personalized treatment strategies. The findings will help shape future HIV treatment approaches for young people.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents and young adults under 21 years old living with HIV in South Africa.
Not a fit: Patients who are not adolescents or young adults, or those who do not have HIV, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved HIV treatment strategies that enhance adherence and health outcomes for adolescents and young adults.
How similar studies have performed: Previous research has shown promising results with long-acting injectable therapies in other populations, suggesting potential success in this novel application for adolescents.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Neilan, Anne — Massachusetts General Hospital
- Study coordinator: Neilan, Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.