Improving HIV treatment and monitoring in South Africa

Simplifying HIV Treatment and Monitoring (STREAM2): Point-of-Care Urine Tenofovir Adherence and Viral Load Testing to Improve HIV Outcomes in South Africa

NIH-funded research University of Washington · NIH-10895299

This study is looking at a new way to help people with HIV stick to their treatment by using quick urine tests to check how well the medicine is working and if patients are taking it as they should, so they can get immediate feedback and support for better health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10895299 on NIH RePORTER

What this research studies

This research focuses on enhancing the management of HIV treatment by implementing point-of-care testing for both viral load and adherence to medication using urine samples. By utilizing innovative testing methods, the study aims to provide immediate feedback to patients and healthcare providers, thereby improving adherence to antiretroviral therapy (ART) and ensuring better health outcomes. The research builds on previous findings that showed increased viral suppression when using point-of-care monitoring, and it seeks to evaluate the effectiveness of these methods in real-world settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are receiving antiretroviral therapy in South Africa.

Not a fit: Patients who are not currently receiving HIV treatment or those who are not located in South Africa may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for people living with HIV by ensuring better adherence to treatment and more effective monitoring of viral load.

How similar studies have performed: Previous studies have shown success with point-of-care monitoring approaches, indicating a promising avenue for improving HIV treatment outcomes.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.