Improving HIV prevention strategies in Botswana
Official title: Evaluation of PrEP implementation strategies for the general population in Botswana
Funded at University of Botswana · NIH-11161430 · Data updated 2026-11-12
This study is all about finding better ways to help people in Botswana learn about and access PrEP, a medication that can prevent HIV, especially focusing on younger folks who are often on the move and use technology a lot.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Botswana NIH-funded |
| Lab location | 1 site (Gaborone, Botswana) |
| Project start | August 5, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $644,944 |
| NIH project number | 5R01MH134784-02 |
| Project ID | NIH-11161430 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include young adults and adolescents in Botswana who are at risk of HIV infection and are seeking preventive options.
✕Less likely to help
Patients who are already HIV positive or those who do not have access to healthcare facilities in Botswana may not benefit from this research.
What this research studies
This research focuses on developing and testing new strategies to improve the implementation of pre-exposure prophylaxis (PrEP) for HIV prevention among the general population in Botswana. It aims to address barriers to PrEP uptake, such as lack of knowledge and social support, particularly targeting younger, mobile, and digitally connected individuals. The study will collaborate with policymakers and healthcare providers to create effective outreach and education programs. By leveraging existing healthcare infrastructure, the research seeks to enhance access to PrEP and ultimately reduce new HIV infections.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rate of new HIV infections in Botswana by improving access to preventive treatments.
How similar studies have gone: Previous research has shown success in implementing PrEP strategies in targeted populations, indicating potential for positive outcomes in broader populations as well.
Where this research is happening
-
University of Botswana
Gaborone, Botswana Active
Researchers
- Principal investigator: Mosepele, Mosepele — University of Botswana
- Study coordinator: Mosepele, Mosepele
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.