Improving HIV prevention for young women in South Africa

Optimizing PrEP implementation and effectiveness among women at high risk for HIV acquisition in South Africa

NIH-funded research Johns Hopkins University · NIH-10895996

This study is all about finding better ways to help young women in South Africa who are at high risk for HIV start and stick with using PrEP, a medication that can help prevent the virus, especially when they need it most.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10895996 on NIH RePORTER

What this research studies

This research focuses on enhancing the use of pre-exposure prophylaxis (PrEP) among young women at high risk for HIV in South Africa. It aims to identify effective strategies that empower these women to start and continue using PrEP, especially during times when their risk of HIV acquisition is heightened. The study will analyze existing data and implement new strategies within a large-scale PrEP delivery program to improve uptake and adherence. By observing program implementation and assessing various interventions, the research seeks to refine approaches that can lead to better health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are young women in South Africa who are at high risk for HIV acquisition.

Not a fit: Patients who are not at risk for HIV or who do not reside in South Africa may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase the effectiveness of HIV prevention efforts among young women in South Africa.

How similar studies have performed: Previous research has shown success in improving PrEP uptake through targeted interventions, indicating that this approach has potential for meaningful impact.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.