Improving HIV prevention for people who inject drugs on medication for opioid use disorder

Optimizing evidence-based HIV prevention targeting people who inject drugs on PrEP

NIH-funded research University of Connecticut Storrs · NIH-10850991

This study is looking to improve HIV prevention for people who inject drugs and are starting treatment for opioid use by helping them better understand and stick to important prevention methods, like PrEP, through fun activities that boost their thinking skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project IDNIH-10850991 on NIH RePORTER

What this research studies

This research aims to enhance HIV prevention strategies specifically for people who inject drugs (PWID) who are starting treatment for opioid use disorder. By using a multiphase optimization strategy, the study will evaluate four key intervention components that focus on cognitive skills such as attention, memory, and information processing. The goal is to improve how these individuals understand and adhere to evidence-based HIV prevention methods, particularly Pre-Exposure Prophylaxis (PrEP). This approach acknowledges the cognitive challenges faced by many PWID, aiming to tailor interventions to better meet their needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who inject drugs and are newly enrolled in medication for opioid use disorder.

Not a fit: Patients who do not inject drugs or are not seeking treatment for opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved adherence to HIV prevention methods among PWID, significantly reducing their risk of HIV infection.

How similar studies have performed: Previous research has shown promise in optimizing interventions for cognitive dysfunction in similar populations, indicating potential for success in this approach.

Where this research is happening

Storrs-Mansfield, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.