Improving HIV prevention for Black cisgender women through better access to PrEP.
Official title: RFA-PS-23-001 - Project PrOVIDE: PrEP Optimization Via Implementation, Dissemination, and Evaluation
Funded at Lurie Children's Hospital of Chicago · NIH-10916157 · Data updated 2026-11-12
This study is all about helping Black women in the U.S. learn more about and access PrEP, a medication that can prevent HIV, by finding better ways to spread awareness and support so they can stay healthy and protected.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 30, 2023 |
| Project end | September 29, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,999,999 |
| NIH project number | 5U01PS005270-02 |
| Project ID | NIH-10916157 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black cisgender women who are at high risk for HIV and may benefit from PrEP.
✕Less likely to help
Patients who are not at risk for HIV or who do not identify as Black cisgender women may not receive benefit from this research.
What this research studies
This research focuses on addressing the significant disparities in the use of pre-exposure prophylaxis (PrEP) for HIV prevention among Black cisgender women in the U.S. The project aims to identify and implement effective strategies to increase PrEP awareness, access, and persistence among this population. By utilizing a combination of education, provider training, and innovative tools, the research seeks to enhance the PrEP care continuum and ensure that women at highest risk receive the support they need. The study will take place across six counties in the U.S., employing implementation science methods to evaluate the effectiveness of these strategies.
Why it matters
Potential benefit: If successful, this research could significantly increase PrEP uptake and reduce HIV transmission rates among Black cisgender women.
How similar studies have gone: While there has been success in increasing PrEP use among men and transgender women, this research focuses on a less explored area, making it a novel approach.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Johnson, Amy Kristen — Lurie Children's Hospital of Chicago
- Study coordinator: Johnson, Amy Kristen
Related research
Other NIH-funded projects on the same topics.
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mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
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TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.