NIH-funded research R01 grant

Improving HIV prevention and substance use support for homeless youth

Official title: Assessing the use of MY-RIDE, a just-in-time adaptive intervention, to Improve HIV prevention and Substance Use in Youth Experiencing Homelessness

Funded at University of Texas Hlth Sci Ctr Houston · NIH-10932983 · Data updated 2026-11-12

This study is testing a helpful mobile program called MY-RIDE that aims to support young people experiencing homelessness in staying safe from HIV and reducing substance use, by sending them personalized messages and feedback based on their needs, all while being easy to access even if they don’t have stable housing.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 21, 2023
Project endJune 30, 2027
Funding year2024
Award (this year)$714,875
NIH project number5R01NR020997-02
Project IDNIH-10932983 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are youth aged 18-25 who are currently experiencing homelessness and are at risk for HIV.

Less likely to help

Patients who are not experiencing homelessness or are outside the age range of 18-25 may not benefit from this research.

What this research studies

This research investigates a mobile health intervention called MY-RIDE, designed to help youth experiencing homelessness (YEH) improve their HIV prevention strategies and reduce substance use. By utilizing real-time assessments, MY-RIDE delivers personalized messages and behavioral feedback to address the unique challenges faced by these young individuals. The intervention incorporates motivational interviewing and shared decision-making techniques, providing support through nurse-led sessions that are accessible even in unstable housing situations. The study will evaluate the effectiveness of MY-RIDE through a randomized trial involving 320 participants aged 18-25 over a period of 12 months.

Why it matters

Potential benefit: If successful, this research could significantly enhance HIV prevention efforts and reduce substance use among homeless youth, leading to better health outcomes.

How similar studies have gone: Previous pilot studies have shown promising results with similar mobile health interventions, indicating potential for success in this approach.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Santa Maria, Diane M. — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Santa Maria, Diane M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.