Improving HIV prevention and care for adolescents and young adults in Uganda

Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

NIH-funded research Mu-Jhu Care · NIH-11395131

The team will try youth-friendly ways to deliver long-acting HIV prevention and better care for 15–24 year-olds in rural and urban Uganda.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care NIH-funded
Lab location1 site (Kampala, Uganda)
Project IDNIH-11395131 on NIH RePORTER

What this research studies

If you join, the project will offer new, community-focused ways to get long-acting HIV prevention shots (cabotegravir) and more supportive care for young people. The study uses simple risk screening to find higher-risk adolescents and combines clinic and community services approved by Uganda's health ministry. It will also deliver a package of youth-tailored supports called SEARCH-Youth to help young people with HIV reach and stay suppressed. The researchers will follow participants in both rural and urban areas to see how these approaches work in everyday settings.

Who could benefit from this research

Good fit: Ideal participants are adolescents and young adults aged about 15–24 in Uganda who are either at high risk for HIV and could benefit from long-acting PrEP or are living with HIV and need support to reach viral suppression.

Not a fit: People older than the study age range, those living outside the participating Ugandan communities, or individuals ineligible for cabotegravir or the care models used may not receive direct benefit from this project.

Why it matters

Potential benefit: Could make HIV prevention easier to use and help more young people achieve lasting viral suppression by offering long-acting medication and youth-focused care closer to where they live.

How similar studies have performed: Long-acting cabotegravir has shown strong protection in prior clinical trials, but combining it with youth-focused delivery models and the SEARCH-Youth package in routine Ugandan settings is relatively new.

Where this research is happening

Kampala, Uganda

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.