NIH-funded research NIH-funded research

Improving HIV prevention and care for adolescents and young adults in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11395131 · Data updated 2026-11-12

The team will try youth-friendly ways to deliver long-acting HIV prevention and better care for 15–24 year-olds in rural and urban Uganda.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$172,619
NIH project number3UG1HD113241-03S2
Project IDNIH-11395131 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young adults aged about 15–24 in Uganda who are either at high risk for HIV and could benefit from long-acting PrEP or are living with HIV and need support to reach viral suppression.

Less likely to help

People older than the study age range, those living outside the participating Ugandan communities, or individuals ineligible for cabotegravir or the care models used may not receive direct benefit from this project.

What this research studies

If you join, the project will offer new, community-focused ways to get long-acting HIV prevention shots (cabotegravir) and more supportive care for young people. The study uses simple risk screening to find higher-risk adolescents and combines clinic and community services approved by Uganda's health ministry. It will also deliver a package of youth-tailored supports called SEARCH-Youth to help young people with HIV reach and stay suppressed. The researchers will follow participants in both rural and urban areas to see how these approaches work in everyday settings.

Why it matters

Potential benefit: Could make HIV prevention easier to use and help more young people achieve lasting viral suppression by offering long-acting medication and youth-focused care closer to where they live.

How similar studies have gone: Long-acting cabotegravir has shown strong protection in prior clinical trials, but combining it with youth-focused delivery models and the SEARCH-Youth package in routine Ugandan settings is relatively new.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.