NIH-funded research NIH-funded research

Improving HIV prevention and care for adolescents and young adults in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11395127 · Data updated 2026-11-12

This project offers new ways to deliver long-acting HIV prevention and stronger treatment support for adolescents and young adults (ages 15–24) in Uganda.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$200,464
NIH project number3UG1HD113241-03S1
Project IDNIH-11395127 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents and young adults aged 15–24 who are at high risk for HIV or who are living with HIV and receive care at participating clinics or community sites in Uganda.

Less likely to help

People younger than 15, older than 24, or those who cannot access the participating sites in Uganda are unlikely to be eligible or directly benefit from this project.

What this research studies

If you join, you may be offered long-acting injectable HIV prevention (cabotegravir) or support services tailored to youth to help you start and stay on prevention or treatment. The project uses new risk screening methods and community-friendly delivery options so services can be provided at clinics or in community settings rather than only at hospitals. For young people living with HIV, a multi-component package called SEARCH-Youth provides life-stage based assessment and support to help reach and keep viral suppression. The study runs in both rural and urban areas of Uganda and combines practical delivery tests with measures of health outcomes to see what works in real-world care.

Why it matters

Potential benefit: If successful, this work could make it easier for young people in Uganda to avoid HIV with long-acting prevention and to achieve and maintain viral suppression if they have HIV.

How similar studies have gone: Large clinical trials have shown long-acting cabotegravir can prevent HIV, and youth-focused delivery models show promise, but combining these approaches in routine Ugandan settings is relatively new.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.