NIH-funded research NIH-funded research

Improving HIV prevention and care for adolescents and young adults in Uganda

Official title: Implementation Science to Understand and Design Stakeholder Informed Innovative Interventions to Improve Adolescent and Youth HIV Prevention and Care Continuums in Rural and Urban Uganda

Funded at Mu-Jhu Care · NIH-11177784 · Data updated 2026-11-12

This project will try offering long-acting HIV prevention injections and youth-focused care to help 15–24-year-olds in Uganda prevent HIV and reach viral suppression if they are living with HIV.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMu-Jhu Care
NIH-funded
Lab location1 site (Kampala, Uganda)
Project startSeptember 8, 2023
Project endAugust 31, 2028
Funding year2025
Award (this year)$364,997
NIH project number5UG1HD113241-03
Project IDNIH-11177784 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young adults (about 15–24 years old) in Uganda who are at high risk for HIV or are living with HIV and need better support to stay on prevention or treatment.

Less likely to help

People outside the 15–24 age range, those not living in participating communities or clinics in Uganda, or individuals with medical reasons that prevent use of cabotegravir may not benefit from this project.

What this research studies

You would be part of work that reaches young people in both rural and urban communities across Uganda to find those at higher risk for HIV and connect them to services. For HIV-negative youth, the project will offer long-acting injectable PrEP (cabotegravir) through community-friendly delivery models to reduce the need for daily pills. For youth living with HIV, teams will provide life-stage based support and the SEARCH-Youth package to help improve treatment adherence and viral suppression. The program uses proven interventions in combination with new screening approaches and implementation methods to make services easier for young people to use.

Why it matters

Potential benefit: If successful, the work could make prevention and treatment easier for young people and increase protection against HIV and rates of viral suppression.

How similar studies have gone: Long-acting injectable PrEP has shown strong protection in clinical trials, but delivering it and combining it with youth-focused support in real-world Ugandan settings is newer and less tested.

Where this research is happening

  • Mu-Jhu Care
    Kampala, Uganda
    Active

Researchers

  • Principal investigator: Musoke, Philippa — Mu-Jhu Care
  • Study coordinator: Musoke, Philippa

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.