Improving HIV Detection and Drug Resistance Testing
HIV Incidence and Drug Resistance Surveillance using Microdrop HIV Sequencing
This project is developing a new, more precise test to track new HIV infections and identify drug-resistant forms of the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11083048 on NIH RePORTER |
What this research studies
Our goal is to create a complete system for real-time tracking of new HIV cases and drug resistance. We are building on our previous success in developing a microdrop HIV sequencing method. This new test, called HIDA, uses a single blood sample to find out how recently someone was infected and to detect any drug resistance mutations, even rare ones. By using advanced sequencing techniques, we can get very accurate information about the virus. This will help public health efforts to better understand and respond to the HIV epidemic.
Who could benefit from this research
Good fit: This work will ultimately benefit individuals living with HIV by improving public health monitoring and informing treatment strategies.
Not a fit: Patients not affected by HIV or those not directly involved in public health surveillance efforts would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective prevention strategies and better-targeted treatments for people living with HIV worldwide.
How similar studies have performed: This is a renewal of a previous project, building upon pioneering accomplishments in developing microdrop HIV sequencing for surveillance.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Lee, Ha Youn — University of Southern California
- Study coordinator: Lee, Ha Youn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.