Improving HIV care for individuals who are not receiving treatment or have high viral loads
Official title: A sequential, adaptive model of differentiated service delivery to reach persons living with HIV who are lost-to-follow-up or who have detectable viral load
Funded at Massachusetts General Hospital · NIH-11013402 · Data updated 2026-11-12
This study is looking for better ways to help people with HIV who aren't getting treatment or have high viral loads by finding out what stops them from accessing care and creating more convenient, community-based options that make it easier to start and stick with their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $481,645 |
| NIH project number | 5R01MH124465-05 |
| Project ID | NIH-11013402 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who are not currently receiving antiretroviral therapy or have a detectable viral load.
✕Less likely to help
Patients who are already successfully engaged in HIV care and have an undetectable viral load may not benefit from this research.
What this research studies
This research focuses on developing and testing new methods to deliver HIV care to individuals who are not currently engaged in treatment or have detectable viral loads. It aims to identify barriers that prevent these individuals from accessing antiretroviral therapy (ART) and to implement adaptive service delivery strategies that are more client-centered. The approach includes community-based ART delivery and incentives to encourage treatment initiation and adherence. By simplifying the process and reducing the need for frequent clinic visits, the research seeks to improve health outcomes for those struggling with HIV.
Why it matters
Potential benefit: If successful, this research could significantly improve access to HIV treatment and health outcomes for individuals who are currently lost to follow-up or have detectable viral loads.
How similar studies have gone: Previous research has shown success with community-based ART delivery and differentiated service delivery models, indicating that this approach has potential for positive outcomes.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Barnabas, Ruanne Vanessa — Massachusetts General Hospital
- Study coordinator: Barnabas, Ruanne Vanessa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.