Improving HIV care and mental health support for adolescents

HIV Engagement and Adolescent Depression Support (HEADS-UP)

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10828328

This study is looking to help teenagers living with HIV in Malawi by making a friendly counseling program that includes support from peers, so they can feel better and stay engaged in their HIV care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10828328 on NIH RePORTER

What this research studies

This research focuses on adolescents living with HIV in sub-Saharan Africa, particularly in Malawi, where engaging these young individuals in HIV care is challenging due to high rates of depression. The study aims to adapt an evidence-based depression counseling intervention called the Friendship Bench to be more youth-friendly and incorporate peer support. By conducting formative research and testing this adapted intervention, the goal is to enhance mental health support and improve engagement in HIV care among adolescents. This approach combines problem-solving therapy with peer support to address both mental health and HIV care needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents living with HIV, particularly those experiencing depression in resource-limited settings.

Not a fit: Patients who are not living with HIV or do not experience mental health challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve mental health and HIV care engagement for adolescents living with HIV.

How similar studies have performed: Previous research has shown success with the Friendship Bench intervention in reducing depression in general populations, but this adaptation for adolescents is novel.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.