Improving hepatitis B treatment strategies in Cote d'Ivoire
Simulation Modeling of Hepatitis B Virus Elimination Strategies in Cote d'Ivoire
This study is looking at ways to make it easier for people in places with limited resources, like sub-Saharan Africa, to get treatment for hepatitis B, by testing different strategies to start treatment that could work well even when money and monitoring are tight.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10890628 on NIH RePORTER |
What this research studies
This research investigates how to simplify hepatitis B management guidelines to enhance treatment access in resource-limited settings, particularly in sub-Saharan Africa. By using simulation modeling, the project aims to evaluate the long-term clinical impacts of various treatment initiation strategies for chronic hepatitis B. The goal is to identify effective approaches that can be implemented despite challenges like high costs and complex monitoring requirements. This work is led by an Infectious Diseases physician with expertise in clinical epidemiology and cost-effectiveness analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with chronic hepatitis B in resource-limited settings, particularly in Cote d'Ivoire.
Not a fit: Patients who do not have chronic hepatitis B or those living outside the targeted geographic area may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved access to hepatitis B treatment for millions of patients in sub-Saharan Africa.
How similar studies have performed: Other research has shown success in using simulation modeling to improve treatment strategies for infectious diseases, indicating that this approach has potential.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mohareb, Amir — Massachusetts General Hospital
- Study coordinator: Mohareb, Amir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.