Improving heart valve repair techniques using advanced engineering methods

Biomechanical Optimization of Cardiac Valve Repair Operations

['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10684179

This study is exploring new ways to improve heart valve repairs for people with heart valve disease by using a special 3D-printed model to test different repair techniques, which could help make surgeries safer and more effective.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10684179 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the repair of heart valves, which is crucial for patients with valvular heart disease. By utilizing a novel 3D-printed simulator that mimics the left heart, researchers can study various valve conditions and repair techniques in detail. The project aims to integrate biomechanical engineering principles into surgical practices, potentially leading to better outcomes and reduced complications for patients undergoing valve repair. Advanced sensors and imaging technologies will be employed to analyze the effectiveness of different repair methods.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with valvular heart disease, particularly those requiring valve repair procedures.

Not a fit: Patients who have already undergone successful valve replacement surgery or those with non-repairable valve conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and durable heart valve repairs, reducing the need for long-term anticoagulation and minimizing the risk of complications.

How similar studies have performed: Previous research has shown promise in using engineering principles to improve surgical techniques, indicating that this approach could yield significant advancements.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.