NIH-funded research R15 grant

Improving heart surgery decisions for patients with stable coronary artery disease

Official title: Multi-modality Image Fusion to Improve Coronary Revascularization in Patients with Stable Coronary Artery Disease

Funded at Michigan Technological University · NIH-10796378 · Data updated 2026-11-12

This study is looking to improve how doctors decide which patients with stable heart disease should have surgery by using special imaging techniques to get a clearer picture of heart function and artery health, helping to ensure that only those who really need it get treated.

More Coronary Artery Disease research and trials

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionMichigan Technological University
NIH-funded
Lab location1 site (Houghton, United States)
Project startDecember 20, 2023
Project endNovember 30, 2026
Funding year2024
Award (this year)$427,307
NIH project number1R15HL172198-01
Project IDNIH-10796378 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with stable coronary artery disease who are considering coronary revascularization.

Less likely to help

Patients with unstable coronary artery disease or those who are not candidates for coronary revascularization may not benefit from this research.

What this research studies

This research aims to enhance the selection process for coronary revascularization in patients with stable coronary artery disease by integrating physiological and anatomical information. The approach involves combining advanced imaging techniques, specifically gated SPECT myocardial perfusion imaging with invasive coronary angiography, to create a comprehensive assessment of heart function and artery conditions. By utilizing machine learning to interpret these combined images, cardiologists can make more informed decisions about which lesions to treat, potentially leading to better patient outcomes. The goal is to ensure that only the most suitable patients undergo surgical interventions, improving overall treatment effectiveness.

Why it matters

Potential benefit: If successful, this research could lead to more precise and effective treatment decisions for patients with coronary artery disease, ultimately improving their health outcomes.

How similar studies have gone: Previous studies have shown that integrating physiological assessments with anatomical imaging can improve treatment outcomes, suggesting a promising avenue for this research.

Where this research is happening

  • Michigan Technological University
    Houghton, United States
    Active

Researchers

  • Principal investigator: Zhou, Weihua — Michigan Technological University
  • Study coordinator: Zhou, Weihua

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.