NIH-funded research Sbir 2 grant

Improving heart support for elderly patients with heart failure and heart attacks

Official title: Native Hemodynamic Measurement as Feedback Control for Mechanical Cardiac Support

Funded at Bridgesource Medical Corporation · NIH-10645215 · Data updated 2026-11-12

This study is looking at ways to make heart support devices better for older patients who are having serious heart problems, like heart attacks or heart failure, by using new technology to measure how well their heart is working, so doctors can make smarter treatment choices and help them recover faster.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionBridgesource Medical Corporation
NIH-funded
Lab location1 site (Austin, United States)
Project startMay 3, 2019
Project endJune 14, 2026
Funding year2023
Award (this year)$1,189,622
NIH project number5R44HL145847-03
Project IDNIH-10645215 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are elderly patients suffering from acute myocardial infarction or acute decompensated heart failure.

Less likely to help

Patients with stable heart conditions or those who are not elderly may not benefit from this research.

What this research studies

This research focuses on enhancing temporary mechanical circulatory support (MCS) devices used for elderly patients experiencing acute heart conditions like heart attacks and heart failure. The study aims to integrate advanced technology that accurately measures heart output, which is crucial for optimizing treatment and determining when to transition patients from temporary support to recovery or permanent solutions. By utilizing a catheter-delivered pump, the research seeks to improve blood flow and reduce the strain on the heart, ultimately aiming for better patient outcomes. The approach involves real-time monitoring of cardiac output to guide treatment decisions effectively.

Why it matters

Potential benefit: If successful, this research could lead to improved management of heart conditions in elderly patients, potentially reducing mortality and enhancing recovery.

How similar studies have gone: Previous research has shown promise in using advanced monitoring technologies for heart conditions, indicating potential success for this novel approach.

Where this research is happening

  • Bridgesource Medical Corporation
    Austin, United States
    Active

Researchers

  • Principal investigator: Porterfield, John E — Bridgesource Medical Corporation
  • Study coordinator: Porterfield, John E

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.