Improving heart rhythm treatment using advanced MRI techniques

Atrial fibrillation ablation assessment and guidance using native-contrast T1 weighted MRI

['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-10881894

This study is looking at a new way to use MRI to help doctors better see the results of a heart procedure for atrial fibrillation, so patients can have safer and more effective treatments that reduce the chances of their heart rhythm problems coming back.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10881894 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the effectiveness of catheter ablation for atrial fibrillation (Afib), a common heart rhythm disorder. It aims to develop a non-contrast MRI method that can accurately identify permanent ablation lesions, which are crucial for successful treatment. By distinguishing between temporary and permanent tissue changes, the research seeks to improve the outcomes of the initial ablation procedure and reduce the recurrence of arrhythmias. Patients may benefit from more effective and safer treatment options for Afib.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with atrial fibrillation who are considering catheter ablation as a treatment option.

Not a fit: Patients with atrial fibrillation who are not candidates for catheter ablation or those who have already undergone multiple unsuccessful ablation procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for atrial fibrillation, reducing the need for repeat procedures and improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to improve outcomes in cardiac procedures, suggesting that this approach may also be effective.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.