NIH-funded research R01 grant

Improving heart pacing during and after surgery with new bioadhesive devices

Official title: Atraumatic Non-fibrotic Epicardial Pacing with E-Bioadhesive Devices

Funded at Massachusetts Institute of Technology · NIH-10893319 · Data updated 2026-11-12

This study is testing a new heart pacing device that uses a special glue to help keep your heart rhythm steady during and after surgery, making it safer and easier for patients like you to recover.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts Institute of Technology
NIH-funded
Lab location1 site (Cambridge, United States)
Project startAugust 1, 2023
Project endJuly 31, 2027
Funding year2024
Award (this year)$603,351
NIH project number5R01HL167947-02
Project IDNIH-10893319 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients scheduled for cardiac surgery who may require temporary pacing due to potential heart rhythm issues.

Less likely to help

Patients who are not undergoing cardiac surgery or do not have a risk of bradyarrhythmias may not benefit from this research.

What this research studies

This research focuses on developing a new type of heart pacing device that uses an electrically conductive bioadhesive to minimize complications during and after cardiac surgery. Traditional pacing leads can cause trauma and inflammation, leading to serious issues like bleeding and device failure. The goal is to create a safer, more effective way to manage heart rhythms in patients undergoing surgery, potentially reducing the risks associated with current methods. Patients who participate may help test this innovative technology, which aims to improve their recovery and overall heart health.

Why it matters

Potential benefit: If successful, this research could lead to safer heart surgery procedures with fewer complications and better outcomes for patients.

How similar studies have gone: Previous research has shown promise in using bioadhesive technologies in medical devices, suggesting potential for success in this novel approach.

Where this research is happening

  • Massachusetts Institute of Technology
    Cambridge, United States
    Active

Researchers

  • Principal investigator: Zhao, Xuanhe — Massachusetts Institute of Technology
  • Study coordinator: Zhao, Xuanhe

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.