Improving heart imaging techniques for children with congenital heart disease
Official title: Dual-Venc 5D flow for Assessment of Congenital Heart Disease in Pediatrics
Funded at Northwestern University at Chicago · NIH-10929301 · Data updated 2026-11-12
This study is looking at new ways to take detailed pictures of blood flow in kids with single ventricle heart disease, so doctors can better understand their heart health and any issues that might come up after surgery.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | July 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $44,711 |
| NIH project number | 5F30HL165805-02 |
| Project ID | NIH-10929301 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years diagnosed with congenital heart disease, particularly those who have undergone the Fontan procedure.
✕Less likely to help
Patients with congenital heart disease who are older than 11 years or those who do not have a history of single ventricle disease may not benefit from this research.
What this research studies
This research focuses on enhancing imaging methods for assessing congenital heart disease, particularly single ventricle disease in pediatric patients. It aims to utilize a novel 4D flow MRI technique that provides detailed, three-dimensional blood flow dynamics over the cardiac cycle, which is crucial for understanding complications that can arise after surgical interventions. The study seeks to improve monitoring methods that are currently limited by user variability and lengthy scan times, especially for young children who may require anesthesia. By refining these imaging techniques, the research hopes to provide better insights into the health of children with congenital heart conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and management of congenital heart disease in children, potentially reducing complications and improving long-term outcomes.
How similar studies have gone: Previous research has shown promise in using 4D flow MRI for studying congenital heart disease, indicating that this approach has potential for significant advancements in patient care.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Weiss, Elizabeth — Northwestern University at Chicago
- Study coordinator: Weiss, Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.