Improving heart imaging techniques for better diagnosis and treatment
Free-breathing and simultaneous multislice cine DENSE myocardial strain imaging
This study is testing a new way to take heart pictures that lets you breathe normally, making it easier for people with heart issues like aortic stenosis and heart failure to get the help they need.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10418633 on NIH RePORTER |
What this research studies
This research focuses on enhancing myocardial strain imaging, a technique used to assess heart function, particularly in patients with conditions like aortic stenosis and heart failure. The study aims to develop a more efficient imaging method that allows for free-breathing during scans, making it easier for patients who struggle with traditional breath-holding techniques. By utilizing advanced MRI technology, the researchers hope to provide real-time analysis of heart strain, which can lead to better patient selection for treatments and improved prognostic evaluations. This innovative approach seeks to overcome current limitations in cardiac imaging, ultimately benefiting patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with aortic stenosis, heart failure, or those undergoing chemotherapy who may experience cardiotoxicity.
Not a fit: Patients with stable heart conditions who do not require advanced imaging techniques may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and convenient heart imaging, improving diagnosis and treatment outcomes for patients with heart conditions.
How similar studies have performed: Previous research has shown promise in improving cardiac imaging techniques, but this specific approach using free-breathing cine DENSE MRI is relatively novel.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Epstein, Frederick H — University of Virginia
- Study coordinator: Epstein, Frederick H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.